Analytical Data
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Gene name
EMG1
- Application
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Alternative Names
EMG1；C2F;Ribosomal RNA small subunit methyltransferase NEP1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92979
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Expression Region
1-244aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAAPSDG FKPRERSGGE QAQDWDALPP KRPRLGAGNK IGGRRLIVVL EGASLETVKV GKTYELLNCD KHKSILLKNG RDPGEARPDI THQSLLMLMD SPLNRAGLLQ VYIHTQKNVL IEVNPQTRIP RTFDRFCGLM VQLLHKLSVR AADGPQKLLK VIKNPVSDHF PVGCMKVGTS FSIPVVSDVR ELVPSSDPIV FVVGAFAHGK VSVEYTEKMV SISNYPLSAA LTCAKLTTAF EEVWGVI
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Molecular Weight
29 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EMG1 is a conserved protein that plays a crucial role in the biosynthesis of ribosomal RNA and the assembly of ribosomes, which are vital for protein synthesis in all living cells. Research into EMG1 has gained prominence due to its involvement in essential cellular processes and its implications in various diseases. This protein is known to participate in the modification of ribosomal RNA and the assembly of the ribosomal small subunit, impacting ribosome biogenesis. Mutations or dysregulation of EMG1 have been linked to certain human diseases, including developmental disorders and cancer, highlighting its potential as a biomarker or therapeutic target. Studies have shown that EMG1 is essential for optimal cell growth and proliferation, emphasizing its importance in cellular metabolism and function. The investigation of EMG1 not only elucidates fundamental aspects of ribosome assembly but also provides insights into the molecular mechanisms underlying its role in disease. Consequently, understanding EMG1's structure, function, and interactions within the ribosomal assembly pathway is critical for advancing knowledge in molecular biology and developing targeted therapeutic strategies.
