Analytical Data
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基因名
ELAVL2
- Application
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别名
ELAVL2；HUB;ELAV-like Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q12926-2
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表达区间
1-346aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMETQLSN GPTCNNTANG PTTINNNCSS PVDSGNTEDS KTNLIVNYLP QNMTQEELKS LFGSIGEIES CKLVRDKITG QSLGYGFVNY IDPKDAEKAI NTLNGLRLQT KTIKVSYARP SSASIRDANL YVSGLPKTMT QKELEQLFSQ YGRIITSRIL VDQVTGISRG VGFIRFDKRI EAEEAIKGLN GQKPPGATEP ITVKFANNPS QKTNQAILSQ LYQSPNRRYP GPLAQQAQRF RFSPMTIDGM TSLAGINIPG HPGTGWCIFV YNLAPDADES ILWQMFGPFG AVTNVKVIRD FNTNKCKGFG FVTMTNYDEA AMAIASLNGY RLGDRVLQVS FKTNKTHKA
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分子量
40 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ELAVL2, also known as HuB, is a member of the ELAV (embryonic lethal abnormal vision) protein family, which plays a crucial role in post-transcriptional regulation of RNA. This protein is characterized by its RNA-binding domains that allow it to interact with various mRNA targets, enhancing their stability, splicing, and translation. Research on ELAVL2 has become increasingly important due to its involvement in neuronal development and function, as well as its potential implications in cancer biology and neurological disorders. Abnormal expression of ELAVL2 has been linked to various pathophysiological conditions, including tumors and neurodegenerative diseases. Studies have shown that ELAVL2 can influence the expression of genes critical for cell survival, proliferation, and differentiation, thus making it a significant target for therapeutic intervention. The production of recombinant ELAVL2 protein enables researchers to explore its biochemical properties and functional mechanism in greater detail, facilitating the identification of specific RNA targets and elucidating the pathways in which it is involved. This research could lead to novel insights into the role of ELAVL2 in health and disease, potentially opening new avenues for treatment strategies that manipulate its activity in various contexts.
