Analytical Data
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Gene name
EFNB2
- Application
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Alternative Names
EFNB2；EPLG5；HTKL；LERK5;Ephrin-B2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P52799
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Expression Region
1-229aa
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AA Sequence
MAVRRDSVWK YCWGVLMVLC RTAISKSIVL EPIYWNSSNS KFLPGQGLVL YPQIGDKLDI ICPKVDSKTV GQYEYYKVYM VDKDQADRCT IKKENTPLLN CAKPDQDIKF TIKFQEFSPN LWGLEFQKNK DYYIISTSNG SLEGLDNQEG GVCQTRAMKI LMKVGQDASS AGSTRNKDPT RRPELEAGTN GRSSTTSPFV KPNPGSSTDG NSAGHSGNNI LGSEVALFA
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Molecular Weight
50 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EFNB2, a member of the ephrin family, plays a crucial role in embryonic development and cell signaling processes. It serves as a ligand for Eph receptors, which are involved in various biological functions, including cell adhesion, migration, and the establishment of boundaries between different tissue types. The study of EFNB2 has garnered attention due to its potential implications in cancer biology, particularly its role in tumor progression and metastasis. Abnormal expression of EFNB2 has been linked to various malignancies, suggesting that it could serve as a biomarker for diagnosis or prognosis. Furthermore, understanding the molecular mechanisms by which EFNB2 exerts its effects could lead to the development of novel therapeutic strategies targeting the Eph/ephrin signaling pathway. Research involving the recombinant production of EFNB2 protein has facilitated detailed studies on its structure-function relationships, interactions with Eph receptors, and downstream signaling events. These insights are critical for elucidating the role of EFNB2 in normal physiological processes and its dysregulation in pathological conditions. Overall, the comprehensive study of EFNB2 recombinant protein holds promise for advancing our understanding of its biological significance and therapeutic potential in various diseases.
