Analytical Data
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Gene name
CELF1
- Application
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Alternative Names
(CELF-1)(50 kDa nuclear polyadenylated RNA-binding protein)(Bruno-like protein 2)(CUG triplet repeat RNA-binding protein 1)(CUG-BP1)(CUG-BP- and ETR-3-like factor 1)(Deadenylation factor CUG-BP)(Embryo deadenylation element-binding protein homolog)(EDEN-BP homolog)(RNA-binding protein BRUNOL-2)
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Species
Human
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Source
E. coli
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Tag
C- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92879
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Expression Region
1-486aa
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Molecular Weight
59.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CELF1, or CUGBP Elav-like family member 1, is an RNA-binding protein that plays a crucial role in post-transcriptional regulation of gene expression. It is known for its involvement in various cellular processes, such as mRNA stability, splicing, and translation. CELF1 has garnered attention due to its significant implications in developmental biology and its association with several diseases, including neurodegenerative disorders and cancer. Abnormal expression or activity of CELF1 has been linked to cellular stress responses and dysregulation of gene expression patterns, suggesting its potential as a therapeutic target. Research on recombinant CELF1 protein allows for a deeper understanding of its molecular functions and interactions with RNA and other proteins. Studies have utilized recombinant CELF1 in various assays to elucidate its role in splicing regulation and mRNA control mechanisms. By generating and characterizing CELF1 recombinant proteins, scientists aim to explore its structural properties and functional domains, paving the way for future investigations into how CELF1 mediates its effects in health and disease. This research not only contributes to the fundamental knowledge of RNA biology but also highlights the potential for CELF1 as a biomarker or target in developing novel therapeutic strategies. As the understanding of CELF1's complexities grows, it may uncover new avenues for addressing the underlying molecular mechanisms of related diseases.
