Analytical Data
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Gene name
KRT2
- Application
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Alternative Names
(Cytokeratin-2e)(CK-2e)(Epithelial keratin-2e)(Keratin-2 epidermis)(Keratin-2e)(K2e)(Type-II keratin Kb2)
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P35908
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Expression Region
1-639aa
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Molecular Weight
72.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KRT2, or Keratin 2, is a member of the keratin family of proteins, which play a critical role in the structural integrity and functionality of epithelial cells. Keratins are essential components of the cytoskeleton, contributing to the mechanical resilience of tissues, especially in the skin and other stratified epithelial surfaces. Research on KRT2 has gained traction due to its implications in various dermatological conditions, including ichthyosis, and its potential role as a biomarker in skin disorders and carcinogenesis. The investigation of KRT2 recombinant proteins has opened avenues for understanding the molecular mechanisms underlying keratinocyte behavior and skin homeostasis. Producing KRT2 in a recombinant form allows for detailed studies of its properties, interactions, and gene regulatory networks in vitro and in vivo, thereby contributing to the development of potential therapeutic strategies for skin diseases. As researchers delve deeper into the biology of KRT2, the potential applications range from disease modeling to regenerative medicine, highlighting the importance of this protein in both fundamental and applied biomedical research.
