Analytical Data
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基因名
LY75
- Application
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别名
LY75；CD205；CLEC13B；Lymphocyte antigen 75
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60449
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LY75 (lymphocyte antigen 75), also known as DEC205, is a C-type lectin receptor predominantly expressed on dendritic cells and some other immune cells. Its primary role involves the recognition and internalization of antigens, facilitating their presentation to T cells, thereby playing a crucial part in immune response regulation. Research into LY75 recombinant protein has gained traction due to its potential applications in immunotherapy and vaccine development. By targeting LY75, scientists aim to enhance antigen delivery and improve the efficacy of vaccines, particularly for cancers and infectious diseases. Furthermore, studies have explored the use of LY75 as a vehicle for delivering therapeutics, allowing for directed activation of the immune system specifically against tumors. Understanding the structural and functional properties of LY75 recombinant protein can provide insights into its immunological roles and pave the way for novel therapeutic strategies. As the field of immunology continues to evolve, LY75 remains a significant focus, with ongoing research aimed at elucidating its mechanisms and optimizing its use in clinical applications.
