Cat: PA1000-861DB

Recombinant Human DENR Protein,His

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Analytical Data

  • 基因名

    DENR

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    DENR;DRP1;Density-regulated Protein

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O43583

  • 表达区间

    2-198aa

  • 氨基酸序列

    AADISESSGADCKGDPRNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK

  • 分子量

    38.0kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

DENR (Density Regulated Protein) is a crucial protein involved in various cellular processes, particularly in relation to translation and response to stress. Research on DENR has gained traction due to its significant role in regulating gene expression through its interaction with ribosomes and mRNA. It has been shown to participate in the translation of specific mRNAs, especially those that code for proteins essential in stress response and cell survival. Understanding DENR's function becomes increasingly important in the context of various diseases, including cancer, where misregulation of protein synthesis can lead to uncontrolled cell proliferation. Furthermore, DENR has been implicated in mechanisms of tumorigenesis and the progression of certain cancers. The exploration of DENR’s structural features and its regulatory pathways holds potential for developing therapeutic strategies that target these processes. This growing body of research highlights the importance of DENR not just as a translational regulator, but also as a potential biomarker or therapeutic target in disease contexts, notably in cancer therapies aimed at restoring the normal regulation of protein synthesis. As scientists continue to uncover the intricacies of DENR’s functions and interactions, there is a burgeoning opportunity for novel insights that could lead to innovative treatment approaches.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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