Analytical Data
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基因名
SLC30A3
- Application
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别名
SLC30A3；ZNT3；Probable proton-coupled zinc antiporter SLC30A3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99726
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表达区间
1-388aa
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氨基酸序列
MEPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAACAVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGILLYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVLGDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQA
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分子量
41.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC30A3, also known as Zinc Transporter 3, is a key member of the SLC30 family of zinc transporters, playing a crucial role in regulating intracellular zinc levels. Zinc is an essential trace element involved in numerous biological processes, including enzyme function, protein synthesis, and cellular signaling. Dysregulation of zinc homeostasis has been implicated in various diseases, including neurodegenerative disorders and diabetes. Research on SLC30A3 has garnered attention due to its specific expression in the brain and pancreatic beta cells, suggesting a vital role in neuronal function and insulin secretion. Understanding the mechanisms by which SLC30A3 regulates zinc transport can provide insights into its physiological functions and potential pathophysiological implications. The generation of recombinant SLC30A3 protein allows for in-depth studies of its transport activity, structural characteristics, and interactions with other cellular components. These investigations are essential for elucidating the transporter's role in health and disease, paving the way for novel therapeutic strategies targeting zinc homeostasis-related conditions.
