Analytical Data
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Gene name
AQP8
- Application
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Alternative Names
AQP8；Aquaporin-8
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O94778
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Expression Region
1-261aa
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AA Sequence
MSGEIAMCEPEFGNDKAREPSVGGRWRVSWYERFVQPCLVELLGSALFIFIGCLSVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLLIRCFIGDGKTRLILKAR
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Molecular Weight
27.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AQP8 (Aquaporin 8) is a member of the aquaporin family of water channel proteins, which play critical roles in water transport across cell membranes. Initially discovered in the kidneys and various other tissues, AQP8 is expressed in several organs including the testis, liver, and brain, suggesting its involvement in diverse physiological processes. Research has indicated that AQP8 facilitates not only water transport but also the permeability of small solutes, thus implicating it in cellular osmoregulation and metabolic processes. Its unique expression patterns and functional properties make it a significant candidate for studying water balance in cells and understanding diseases related to water homeostasis, such as renal disorders and some types of edema. Moreover, AQP8 has been linked to reproductive health, particularly in sperm maturation and motility, highlighting its importance in male fertility. Recent advances in recombinant protein technology have enabled the production of AQP8 in heterologous systems, facilitating structural and functional studies that can elucidate its mechanisms of action. Understanding the functional dynamics of AQP8 through recombinant protein research is pivotal, as it could lead to novel therapeutic targets for manipulating fluid balance in pathological conditions and enhancing our comprehension of aquaporins' roles in human health.
