Analytical Data
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基因名
BMP8B
- Application
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别名
BMP8B；BMP8；Bone morphogenetic Protein 8B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P34820
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表达区间
274-362aa
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氨基酸序列
KKSNELPQANRLPGIFDDVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQ GYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPDAV
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分子量
35 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BMP8B (Bone Morphogenetic Protein 8B) is a member of the BMP family, which plays a critical role in various biological processes, including bone formation, tissue regeneration, and cellular differentiation. It is particularly significant in the context of reproductive biology and metabolism, where it has been implicated in neural regulation and energy homeostasis. Research indicates that BMP8B is involved in the development and function of brown adipose tissue and may influence metabolic pathways through its role in regulating thermogenesis and energy expenditure. Given its multifaceted roles, recombinant BMP8B protein has gained attention for its potential therapeutic applications in obesity, diabetes, and other metabolic disorders. Understanding its structure, function, and signaling pathways is crucial for elucidating its biological effects and developing targeted therapies. As scientists seek to leverage the benefits of BMP8B in clinical settings, studies on its recombinant form help unravel its mechanisms of action, paving the way for innovative strategies in metabolic disease management and regenerative medicine. This growing interest in BMP8B necessitates comprehensive research to optimize its production, stability, and bioactivity for future applications.
