Analytical Data
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基因名
ST2
- Application
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别名
ST2；DER4；ST2；T1；Interleukin-1 receptor-like 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q01638
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表达区间
19-323aa
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氨基酸序列
KFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFAS GQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLM YSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVI DNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPA QNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQ EEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRL SRKNP
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分子量
61 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ST2, a member of the interleukin (IL)-1 receptor family, has garnered significant interest in biomedical research due to its dual role in immune regulation and cardiovascular health. Initially identified as a receptor for IL-33, ST2 is now recognized for its involvement in various physiological and pathological processes, including allergic responses, asthma, heart failure, and atherosclerosis. The soluble form of ST2 (sST2) is released into circulation and has been shown to serve as a biomarker for endothelial dysfunction and myocardial stress. Elevated sST2 levels have been associated with poor outcomes in patients with heart failure and have potential implications in predicting disease progression. The recombinant ST2 protein is being explored for its therapeutic potential, as modulating ST2 signaling may provide new strategies for treating inflammatory and cardiovascular diseases. Understanding the molecular mechanisms of ST2 and its interactions in different contexts remains a key area of investigation, with the ultimate goal of leveraging ST2-targeted therapies to improve patient outcomes in various conditions.
