Analytical Data
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基因名
BMP5
- Application
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别名
BMP5;Bone morphogenetic Protein 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P22003-1
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表达区间
324-454aa
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氨基酸序列
QNRNKSSSHQ DSSRMSSVGD YNTSEQKQAC KKHELYVSFR DLGWQDWIIA PEGYAAFYCD GECSFPLNAH MNATNHAIVQ TLVHLMFPDH VPKPCCAPTK LNAISVLYFD DSSNVILKKY RNMVVRSCGC H
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分子量
42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Bone morphogenetic protein 5 (BMP5) is a member of the transforming growth factor-beta (TGF-β) superfamily, known for its crucial role in bone and cartilage development. Research into BMP5 has gained attention due to its involvement in various biological processes, including embryonic development, tissue regeneration, and the maintenance of skeletal homeostasis. Mutations or dysregulation of BMP5 have been linked to a range of skeletal disorders and developmental abnormalities, highlighting its significance in medical research. The production of recombinant BMP5 proteins enables scientists to study their biological functions in detail, paving the way for potential therapeutic applications in regenerative medicine and orthopedics. By understanding the signaling pathways and mechanisms through which BMP5 operates, researchers aim to develop innovative treatments for conditions such as osteoarthritis, fractures, and other skeletal diseases, ultimately improving patient care and outcomes. Thus, BMP5 recombinant protein serves as a pivotal tool in elucidating the complexities of bone biology and advancing therapeutic strategies.












