Analytical Data
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Gene name
BABAM1
- Application
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Alternative Names
BABAM1；C19orf62；MERIT40；NBA1；BRISC and BRCA1-A complex member 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TDN4
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Expression Region
1-329aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMEVAEPS SPTEEEEEEE EHSAEPRPRT RSNPEGAEDR AVGAQASVGS RSEGEGEAAS ADDGSLNTSG AGPKSWQVPP PAPEVQIRTP RVNCPEKVII CLDLSEEMSL PKLESFNGSK TNALNVSQKM IEMFVRTKHK IDKSHEFALV VVNDDTAWLS GLTSDPRELC SCLYDLETAS CSTFNLEGLF SLIQQKTELP VTENVQTIPP PYVVRTILVY SRPPCQPQFS LTEPMKKMFQ CPYFFFDVVY IHNGTEEKEE EMSWKDMFAF MGSLDTKGTS YKYEVALAGP ALELHNCMAK LLAHPLQRPC QSHASYSLLE EEDEAIEVEA TV
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Molecular Weight
39 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BABAM1, a protein associated with the regulation of the cellular response to DNA damage, has garnered increasing attention in molecular biology and cancer research. This protein, part of the larger protein complex involved in double-strand break repair, plays a crucial role in homologous recombination and the maintenance of genomic stability. Recent studies have suggested that dysregulation of BABAM1 may contribute to various malignancies, making it a potential target for therapeutic interventions. The investigation of recombinant BABAM1 protein serves several purposes, including elucidating its functional mechanisms, understanding its interactions with other proteins in the DNA damage response pathway, and assessing its potential as a biomarker for cancer diagnosis or prognosis. Furthermore, the recombinant production of BABAM1 allows for detailed structural and biochemical studies, facilitating the exploration of small molecules or peptides that could modulate its activity. By advancing our understanding of BABAM1's role in cellular processes, researchers aim to develop novel strategies for cancer treatment, ultimately improving patient outcomes.
