Cat: PA1000-125DB

Recombinant Human ALDH3A1 Protein,His

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Analytical Data

  • Gene name

    ALDH3A1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ALDH3A1;ALDH3;Aldehyde dehydrogenase. dimeric NADP-preferring

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P30838

  • Expression Region

    2-453aa

  • AA Sequence

    SKISEAVKR ARAAFSSGRT RPLQFRIQQL EALQRLIQEQ EQELVGALAA DLHKNEWNAY YEEVVYVLEE IEYMIQKLPE WAADEPVEKT PQTQQDELYI HSEPLGVVLV IGTWNYPFNL TIQPMVGAIA AGNSVVLKPS ELSENMASLL ATIIPQYLDK DLYPVINGGV PETTELLKER FDHILYTGST GVGKIIMTAA AKHLTPVTLE LGGKSPCYVD KNCDLDVACR RIAWGKFMNS GQTCVAPDYI LCDPSIQNQI VEKLKKSLKE FYGEDAKKSR DYGRIISARH FQRVMGLIEG QKVAYGGTGD AATRYIAPTI LTDVDPQSPV MQEEIFGPVL PIVCVRSLEE AIQFINQREK PLALYMFSSN DKVIKKMIAE TSSGGVAAND VIVHITLHSL PFGGVGNSGM GSYHGKKSFE TFSHRRSCLV RPLMNDEGLK VRYPPSPAKM TQH

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ALDH3A1 (Aldehyde Dehydrogenase 3A1) is an important enzyme that plays a crucial role in cellular detoxification by metabolizing aldehydes, which are harmful byproducts of various metabolic processes. This enzyme is particularly significant in the context of cancer, where it is often found to be overexpressed, contributing to tumor cell survival by neutralizing cytotoxic aldehydes and protecting against oxidative stress. Research on recombinant ALDH3A1 protein has gained momentum due to its potential applications in cancer therapy and drug development. By producing ALDH3A1 in a recombinant form, scientists aim to elucidate its structure-function relationships, understand its substrate specificity, and investigate its involvement in cancer metabolism. The recombinant protein can be used to develop assays for screening potential inhibitors or to study the effects of ALDH3A1 on cellular systems. Furthermore, exploring the polymorphisms and expression patterns of ALDH3A1 can provide insights into individual susceptibility to cancer and responses to chemotherapy. Overall, the study of recombinant ALDH3A1 protein holds promise for advancing our understanding of its biological functions and therapeutic potentials in oncology.

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