Analytical Data
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Gene name
pmpD
- Application
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Alternative Names
Polymorphic membrane protein D
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Species
Chlamydia trachomatis
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O84818
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Expression Region
1244-1531aa
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Molecular Weight
47.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PmpD is a significant protein involved in the pathogenicity of various bacterial species, notably in Chlamydia species, which are infamous for causing human infections. Research into PmpD has gained momentum due to its potential role as a virulence factor and its involvement in the immune evasion strategies employed by these pathogens. The protein is thought to facilitate the bacteria's interaction with host cells, promoting infection and chronic disease states. Understanding the structure and function of PmpD provides insight into its mechanisms of action and its potential as a target for therapeutic intervention. The ongoing studies aim to elucidate the molecular pathways that PmpD influences, as well as its interactions with the host immune system, thereby revealing possible strategies for vaccine development or novel antimicrobial therapies. Additionally, characterizing the recombinant PmpD protein continues to be essential for advancing our knowledge of bacterial pathogenesis and improving diagnostic tools. As the research progresses, it holds promise for contributing to more effective approaches in managing infections caused by Chlamydia and related pathogens.
