Cat: PA1000-61DB

Recombinant Human ADH1A Protein,His

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Analytical Data

  • 基因名

    ADH1A

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ADH1A;ADH1;Alcohol dehydrogenase 1A

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P07327

  • 表达区间

    1-375aa

  • 氨基酸序列

    MGSSHHHHHHSSGLVPRGSHMSTAGKVIKCKAAVLWELKKPFSIEEVEVA PPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEG VTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSR FTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKF AKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL LCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVP KLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILMF

  • 分子量

    42 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

The study of ADH1A (Alcohol Dehydrogenase 1A) recombinant protein has garnered significant attention due to its vital role in alcohol metabolism and potential implications in various health-related areas, including alcoholism, liver disease, and metabolic disorders. ADH1A is a key enzyme in the conversion of ethanol to acetaldehyde, a critical step in alcohol detoxification, making it a significant target for understanding individual variations in alcohol tolerance and susceptibility to alcohol-related diseases. The recombinant expression of ADH1A allows researchers to obtain large quantities of the protein for in-depth functional studies, including enzymatic activity assays, structural analysis, and interaction with inhibitors or cofactors. Advances in molecular cloning and protein purification techniques have facilitated the generation of highly purified ADH1A, enabling investigations into its kinetic properties and regulation. Furthermore, studying ADH1A at the molecular level can illuminate the mechanisms underlying its polymorphisms, which are known to influence alcohol metabolism in different populations. This research can lead to better therapeutic strategies for managing alcohol-related conditions and contribute to the development of personalized medicine approaches based on genetic predisposition to alcohol's effects. Additionally, exploring the potential role of ADH1A in other metabolic pathways further emphasizes its importance in human health and disease. As our understanding of this enzyme continues to evolve, ADH1A recombinant protein serves as a crucial tool not only for basic science research but also for developing potential clinical applications that address the challenges associated with alcohol consumption and its metabolic consequences.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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