Analytical Data
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基因名
AK3
- Application
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别名
AK3；AK3L1；AK6；AKL3L；GTP:AMP phosphotransferase AK3. mitochondrial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UIJ7
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表达区间
1-227aa
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氨基酸序列
Adenylate kinase 3 alpha-like 1; Adenylate kinase 3; Adenylate kinase 3. formerly; adenylate kinase 6. adenylate kinase 3 like 1; AK 3; AK3; AK3. formerly; AK3L1; AK4; AK4. mouse. homolog of; AK6; AKL3L; AKL3L1; FIX; GTP:AMP phosphotransferase; GTP:AMP phosphotransferase. mitochondrial; KAD3_HUMAN; mitochondrial; OTTHUMP00000021015; OTTHUMP00000021016; RP11 6J24.4
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分子量
32.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The AK3 protein, known as adenylate kinase 3, plays a crucial role in cellular energy metabolism by catalyzing the conversion of ATP and AMP to ADP, thus maintaining the balance of nucleotide levels within the cell. Recent studies have highlighted its significance in various physiological processes, including muscle contraction, signal transduction, and apoptosis. Dysregulation of AK3 has been implicated in several diseases, including cancer, where it may contribute to altered energy homeostasis and cellular proliferation. Research has also indicated that AK3 may be involved in the mitochondrial dynamics and cellular response to stress. As a result, the recombinant expression and characterization of AK3 have gained attention in the field of molecular biology and biotechnology. Investigating AK3 through recombinant techniques allows for in-depth studies of its structure-function relationship and its interactions with other cellular components. Understanding these dynamics could potentially lead to novel therapeutic strategies targeting AK3 in disease contexts, making it a promising target for drug development and intervention strategies aimed at restoring metabolic balance.
