Analytical Data
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Gene name
NOMO1
- Application
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Alternative Names
Nomo; PM5
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15155
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Expression Region
Phe365~Ala542
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Molecular Weight
25kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NOMO1, or Nodal modulator 1, is a key protein involved in the regulation of Nodal signaling pathways, which are essential for various developmental processes, including embryogenesis and organogenesis. Nodal is a member of the transforming growth factor-beta (TGF-β) superfamily, influencing cell differentiation and proliferation. Dysregulation of Nodal signaling has been associated with several developmental disorders and diseases, including cancer. NOMO1 acts as a pivotal modulator, interacting with specific receptors to fine-tune the Nodal signaling pathway. This research has gained increasing attention due to its potential implications in developmental biology and regenerative medicine. By elucidating the structure and function of NOMO1 through recombinant protein studies, researchers aim to understand its precise role in Nodal signaling. This knowledge could lead to novel therapeutic strategies for conditions linked to Nodal dysregulation. The production of NOMO1 as a recombinant protein allows for detailed biochemical analysis, including its interactions with Nodal and other pathway components, paving the way for potential applications in targeted therapies and biomarker development. Overall, studying NOMO1 not only enhances our understanding of fundamental biological processes but also opens new avenues for addressing diseases associated with aberrant Nodal signaling.
