Analytical Data
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基因名
TXNDC12
- Application
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别名
Endoplasmic reticulum resident protein 19 Short name: ER protein 19 Short name: ERp19 Thioredoxin-like protein p19
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种属
Mouse
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表达系统
Yeast
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9CQU0
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表达区间
25-170aa
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分子量
18.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The TXNDC12 protein, a member of the thioredoxin-like family, has attracted significant interest due to its potential role in redox regulation and cellular processes such as apoptosis and stress response. Emerging research indicates that TXNDC12 may be involved in various pathological conditions, including cancer and neurodegenerative diseases, where it may affect protein folding and antioxidant defense mechanisms. Studies have shown that TXNDC12 can modulate the activity of crucial signaling pathways, thus influencing cell survival and proliferation. Given its involvement in these processes, understanding the structure and function of TXNDC12 is essential for uncovering its biological roles and therapeutic potentials. Efforts to produce recombinant TXNDC12 protein have focused on elucidating its biochemical properties and interactions with other cellular molecules. By employing techniques such as site-directed mutagenesis and crystallography, researchers aim to characterize the protein's active sites and functional domains. This research not only contributes to a deeper understanding of thioredoxin family proteins but also paves the way for developing targeted interventions in diseases where TXNDC12 is implicated. Overall, studying TXNDC12's molecular characteristics and biological functions could reveal critical insights into the maintenance of cellular redox homeostasis and the broader implications for human health.












