Analytical Data
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Gene name
VAPA
- Application
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Alternative Names
VAP-A; VAP33; hVAP-33; 33 kDa VAMP-associated protein
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9P0L0
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Expression Region
Met~Met132
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Molecular Weight
17kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
VAPA (VAMP-associated protein A) is a critical protein involved in various cellular processes, particularly in membrane trafficking and lipid metabolism. Research into VAPA has gained momentum due to its association with the regulation of intracellular vesicle fusion and its role in the formation of membrane contact sites between organelles, such as the endoplasmic reticulum and mitochondria. These processes are vital for maintaining cellular homeostasis and signaling, as well as for the proper functioning of the secretory pathway. Additionally, VAPA has been implicated in several pathological conditions, including neurodegenerative diseases and metabolic disorders, making it a significant target for therapeutic interventions. Increased understanding of VAPA's structure and function, particularly through the study of its recombinant protein, may lead to insights into cellular mechanisms underlying these diseases and uncover potential avenues for drug development. Overall, the study of VAPA and its recombinant forms represents a promising area of research that bridges cell biology and medicine, aiming to elucidate its multifaceted roles within the cell and its potential impact on health and disease.
