Analytical Data
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基因名
SLC6A2
- Application
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别名
Slc6a2; SLC6A5; Sodium dependent noradrenaline transporter
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种属
Human
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表达系统
E. coli
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标签
His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P23975
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表达区间
1-617aa
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氨基酸序列
MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCPLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFVQRRLKRGDADPVA
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分子量
69,3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
SLC6A20, a member of the solute carrier family, encodes a sodium-dependent amino acid transporter primarily involved in the reabsorption of proline and other amino acids in the renal tubules and intestines. Research into SLC6A20 has garnered attention due to its critical role in amino acid transport and potential implications in various physiological processes and pathologies. Mutations or dysregulation of SLC6A20 have been linked to disorders such as Hartnup disorder, characterized by the impaired transport of essential amino acids, leading to clinical manifestations like deficiency in essential amino acids and associated symptoms. Moreover, the transporter is believed to play a role in the uptake of proline in the context of kidney function and gastrointestinal health. The study of SLC6A20 at the protein level, particularly through the production of recombinant SLC6A20 protein, allows researchers to investigate its functional properties, transport kinetics, and interaction with potential substrates and inhibitors. This research is crucial for understanding the transport mechanisms mediated by SLC6A20, as well as for identifying therapeutic targets for disorders related to amino acid transport. Additionally, recombinant SLC6A20 proteins serve as valuable tools in drug discovery, enabling the exploration of compounds that may enhance or inhibit its function, thereby contributing to the development of novel therapeutic strategies for metabolic disorders and enhancing our understanding of amino acid homeostasis in human health.
