Analytical Data
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Gene name
GMCL1L
- Application
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Alternative Names
GMCL2; GCL; GMCL1L; GMCL1P1Germ cell-less protein-like 2; Germ cell-less protein-like 1-like
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NEA9
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Expression Region
1-526aa
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AA Sequence
MGSSSSRVLGQPRRALAQQEQGARARGSARRPDTGDDAASYGFCYCPGSHKRKRSSGACRYCDPDSHREEHEEEGDKQQPLLNTPARKKLRSTSKYIYQTLFLNGENSDIKICALGEEWRLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDVDALQVAFGSLYRDDVLIKPSRVVAILAAACMLQLDGLIQQCGETMKETINVKTVCGYYTSVEIYGLDSVKKKCLEWLLNNLMTHQNVKLFKELGINVMKQLIGSSNLFVMQVEMDVYTTLKKWMFLQLVPSWNGSLKQLLTETDVWFSKQRKDFEGMAFLETEPGKPFVSVFRHLRLQYIISDLASARIIEQDGIVPSEWLSSVYKQQWFAMLRAEQDHEVGPQEINKEDLEGSSMRCGRKLAKDGEYYWCWTGFNFGFDLLVIYTNGYIIFKRNTLNQPCSGSVSLRPRRSIAFRLRLASFDSSGKLVCSRTTGYQILILKKDQEQVVMNLDSRFLTFPLYICCNFLYISPEKGIENNRHPEDPEN
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Molecular Weight
86.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GMCL1L (Germ Cell-Like 1-Like) is a protein that has garnered interest in the field of developmental biology and reproductive medicine due to its potential roles in germ cell development and differentiation. While research on germ cell formation has illuminated critical signaling pathways and genetic determinants, the specific functions and mechanisms of GMCL1L remain largely unexplored. This protein is thought to be involved in early embryogenesis and the formation of gametes, which are crucial for fertility. The exploration of GMCL1L as a recombinant protein presents an opportunity to better understand its biological activities, interactions with other cellular components, and its implications in reproductive health. Researchers aim to elucidate the structure-function relationships of GMCL1L by producing it in a recombinant form, allowing for detailed biochemical characterization and functional assays. Understanding GMCL1L's role could not only enhance our comprehension of germ cell biology but also potentially lead to therapeutic advancements for reproductive disorders. Investigating GMCL1L further may reveal novel targets for interventions in fertility-related issues, paving the way for innovative reproductive technologies and treatments.











