Analytical Data
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Gene name
GLTSCR2
- Application
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Alternative Names
Glioma tumor suppressor candidate region gene 2 protein; GLTSCR2; GSCR2_HUMAN; p60; PICT1; protein interacting with carboxyl terminus 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NZM5
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Expression Region
1-478aa
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AA Sequence
MAAGGSGVGGKRSSKSDADSGFLGLRPTSVDPALRRRRRGPRNKKRGWRRLAQEPLGLEVDQFLEDVRLQERTSGGLLSEAPNEKLFFVDTGSKEKGLTKKRTKVQKKSLLLKKPLRVDLILENTSKVPAPKDVLAHQVPNAKKLRRKEQLWEKLAKQGELPREVRRAQARLLNPSATRAKPGPQDTVERPFYDLWASDNPLDRPLVGQDEFFLEQTKKKGVKRPARLHTKPSQAPAVEVAPAGASYNPSFEDHQTLLSAAHEVELQRQKEAEKLERQLALPATEQAATQESTFQELCEGLLEESDGEGEPGQGEGPEAGDAEVCPTPARLATTEKKTEQQRRREKAVHRLRVQQAALRAARLRHQELFRLRGIKAQVALRLAELARRRRRRQARREAEADKPRRLGRLKYQAPDIDVQLSSELTDSLRTLKPEGNILRDRFKSFQRRNMIEPRERAKFKRKYKVKLVEKRAFREIQL
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Molecular Weight
80.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GLTSCR2 (GLTSCR protein 2) is a gene that encodes a protein involved in various cellular processes, including cell proliferation, apoptosis, and gene regulation. Research on GLTSCR2 has gained traction due to its potential implications in cancer biology and other diseases. It is believed that GLTSCR2 functions as a tumor suppressor, and its loss or dysfunction may contribute to the progression of several types of cancer. Studies have shown that GLTSCR2 interacts with key signaling pathways, including those related to cell cycle regulation and stress responses, highlighting its role in maintaining cellular homeostasis. Moreover, the protein’s involvement in RNA metabolism and its potential to modulate gene expression further underscores its significance in cellular functions. Investigating GLTSCR2 and its recombinant forms has become critical for understanding the underlying mechanisms of tumorigenesis and exploring therapeutic avenues. Researchers are particularly interested in the protein's structure and function, aiming to elucidate how its alterations may contribute to disease states. The production of recombinant GLTSCR2 enables detailed studies, such as structural analysis and functional assays, which can provide insights into its interactions and biological activity. Given its promise as a therapeutic target, continued research on GLTSCR2 is essential for developing novel strategies in cancer treatment and understanding the broader implications of its regulatory roles in human health.
