Analytical Data
-
Gene name
FOXK2
- Application
-
Alternative Names
FOXK2. ILF. ILF1
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q01167
-
Expression Region
1-660aa
-
AA Sequence
MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN
-
Molecular Weight
69 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOXK2 (Forkhead Box K2) is a member of the Forkhead box family of transcription factors, which are characterized by a distinctive winged-helix DNA-binding domain. Research into FOXK2 has gained momentum due to its significant roles in various biological processes, including cell proliferation, differentiation, and apoptosis. It has been associated with several diseases, particularly cancer, where it is implicated in tumor progression and metastasis. The ability to regulate gene expression makes FOXK2 a potential target for therapeutic intervention. Studies have suggested that FOXK2 exerts its effects by modulating key signaling pathways, such as the Wnt/β-catenin pathway and the epithelial-mesenchymal transition (EMT), which are critical in cancer biology. Recombinant FOXK2 protein is increasingly being employed in research to elucidate its functional characteristics and mechanisms of action, allowing for a deeper understanding of its role within cellular contexts. The production and characterization of FOXK2 as a recombinant protein enable detailed biochemical studies, including protein-protein interactions, downstream target identification, and its impact on various cellular functions. This research is essential not only for basic scientific knowledge but also for the potential development of FOXK2-targeted therapies in cancer treatment and other diseases where its dysregulation plays a pivotal role.
