Analytical Data
-
基因名
GATA2
- Application
-
别名
Gata2Endothelial transcription factor GATA-2
-
种属
Mouse
-
表达系统
E. coli
-
标签
N-terminal His and TRxA Tag
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O09100
-
表达区间
1-480aa
-
氨基酸序列
MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDS QGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAA AAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAAGGSGGGSGSSVASLTPT AAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSVARGEDKDGVKYQVS LSESMKMEGGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYGSSLFHPGGF LGGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHK MNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYK LHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKGAECFEELSKCMQEKSPPFSAAA LAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
-
分子量
65.5kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GATA2 is a transcription factor that plays a crucial role in hematopoiesis and the development of various tissues, including the immune system. Mutations in the GATA2 gene have been linked to a range of immunodeficiencies and hematological disorders, such as myelodysplastic syndromes and acute myeloid leukemia. Research on GATA2 recombinant proteins has gained significance in understanding its functional mechanisms and the regulatory pathways it governs. By producing recombinant GATA2 protein, researchers can explore its binding affinity to DNA, identify target genes, and elucidate its interactions with other transcription factors and cofactors. This understanding can shed light on how GATA2 mutations lead to disease and potentially uncover new therapeutic targets. Additionally, the development of GATA2-based recombinant proteins may facilitate novel approaches in gene therapy and regenerative medicine. Given the protein's pivotal role in cellular processes, comprehensive studies on its function and structure can provide insights into the molecular basis of blood disorders and foster advancements in targeted treatments. The ongoing research in this field not only promises to enhance our understanding of GATA2's physiological roles but also holds the potential for significant clinical implications in addressing GATA2-related pathologies.
