Analytical Data
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基因名
APOA1BP
- Application
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别名
APOA1BP；AIBP；APOA1BP；YJEFN1；NAD(P)H-hydrate epimerase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NCW5
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表达区间
1-288aa
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氨基酸序列
MSRLRALLGL GLLVAGSRVP RIKSQTIACR SGPTWWGPQR LNSGGRWDSE VMASTVVKYL SQEEAQAVD QELFNEYQFS VDQLMELAGL SCATAIAKAY PPTSMSRSPP TVLVICGPGN NGGDGLVCA RHLKLFGYEP TIYYPKRPNK PLFTALVTQC QKMDIPFLGE MPAEPMTIDE LYELVVDAI FGFSFKGDVR EPFHSILSVL KGLTVPIASI DIPSGWDVEK GNAGGIQPDL LISLTAPKK SATQFTGRYH YLGGRFVPPA LEKKYQLNLP PYPDTECVYR LQ
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分子量
31 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
APOA1BP, or Apolipoprotein A1 Binding Protein, has garnered significant interest in recent years due to its potential role in lipid metabolism and cardiovascular health. This protein is known to interact with apolipoprotein A1, a major component of high-density lipoprotein (HDL), which is crucial for cholesterol transport and homeostasis. Research suggests that APOA1BP may influence HDL functionality, thereby affecting the reverse cholesterol transport pathway, which is vital for preventing atherosclerosis and promoting vascular health. Dysregulation of this protein has been implicated in various lipid disorders, thus stimulating investigations into its molecular mechanisms and potential therapeutic applications. Recent studies have focused on the recombinant expression and characterization of APOA1BP to better understand its biological functions and interactions with other lipid-associated proteins. By employing advanced techniques such as site-directed mutagenesis and structural biology approaches, researchers aim to elucidate how modifications in APOA1BP can impact lipid profiles and cardiovascular risks. The ultimate goal of this research is to identify potential biomarkers for cardiovascular diseases and develop novel strategies for treatment, highlighting the significance of APOA1BP in the landscape of metabolic health and disease.
