Cat: PA1000-8813

Recombinant Human APOA1BP Protein,His

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Analytical Data

  • Gene name

    APOA1BP

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    APOA1BP;AIBP;APOA1BP;YJEFN1;NAD(P)H-hydrate epimerase

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8NCW5

  • Expression Region

    1-288aa

  • AA Sequence

    MSRLRALLGL GLLVAGSRVP RIKSQTIACR SGPTWWGPQR LNSGGRWDSE VMASTVVKYL SQEEAQAVD QELFNEYQFS VDQLMELAGL SCATAIAKAY PPTSMSRSPP TVLVICGPGN NGGDGLVCA RHLKLFGYEP TIYYPKRPNK PLFTALVTQC QKMDIPFLGE MPAEPMTIDE LYELVVDAI FGFSFKGDVR EPFHSILSVL KGLTVPIASI DIPSGWDVEK GNAGGIQPDL LISLTAPKK SATQFTGRYH YLGGRFVPPA LEKKYQLNLP PYPDTECVYR LQ

  • Molecular Weight

    31 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

APOA1BP, or Apolipoprotein A1 Binding Protein, has garnered significant interest in recent years due to its potential role in lipid metabolism and cardiovascular health. This protein is known to interact with apolipoprotein A1, a major component of high-density lipoprotein (HDL), which is crucial for cholesterol transport and homeostasis. Research suggests that APOA1BP may influence HDL functionality, thereby affecting the reverse cholesterol transport pathway, which is vital for preventing atherosclerosis and promoting vascular health. Dysregulation of this protein has been implicated in various lipid disorders, thus stimulating investigations into its molecular mechanisms and potential therapeutic applications. Recent studies have focused on the recombinant expression and characterization of APOA1BP to better understand its biological functions and interactions with other lipid-associated proteins. By employing advanced techniques such as site-directed mutagenesis and structural biology approaches, researchers aim to elucidate how modifications in APOA1BP can impact lipid profiles and cardiovascular risks. The ultimate goal of this research is to identify potential biomarkers for cardiovascular diseases and develop novel strategies for treatment, highlighting the significance of APOA1BP in the landscape of metabolic health and disease.

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