Analytical Data
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Gene name
FATP1
- Application
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Alternative Names
FATP1；ACSVL5；FATP1；Long-chain fatty acid transport Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6PCB7
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Expression Region
1-646aa
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AA Sequence
MRAPGAGAASVVSLALLWLLGLPWTWSAAAALGVYVGSGGWRFLRIVCKT ARRDLFGLSVLIRVRLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGT GECWTFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAK AGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSL IKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGMDDRLFYIYTS GTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIG VGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVR EAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMD GKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLL VGQINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELG YMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGK AGMAAVADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQ KTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL
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Molecular Weight
98 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FATP1, or fatty acid transport protein 1, is a membrane protein that plays a critical role in the uptake and transport of long-chain fatty acids across cell membranes. Understanding FATP1 is essential due to its involvement in various physiological processes, including lipid metabolism, energy homeostasis, and insulin sensitivity. Dysregulation of FATP1 has been linked to metabolic disorders, such as obesity and type 2 diabetes, making it a significant target for therapeutic interventions. The recombinant production of FATP1 is crucial for in-depth studies of its structure and function, particularly to explore the mechanisms by which it facilitates fatty acid transport and its interactions with other proteins. By utilizing techniques such as recombinant DNA technology, researchers can produce large quantities of FATP1 for biochemical analyses and functional assays. This research contributes to a better understanding of how FATP1 operates at the molecular level and its potential role in metabolic diseases. Furthermore, elucidating the structure-function relationship of FATP1 could pave the way for the development of novel drugs aimed at modulating fatty acid metabolism, thereby providing new strategies for managing obesity and related metabolic syndromes.
