Analytical Data
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基因名
UNC5CL
- Application
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别名
UNC5CL; ZUDUNC5C-like Protein; Protein unc-5 homolog C-like; ZU5 and death domain-containing Protein
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IV45
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表达区间
1-518 aa
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氨基酸序列
MCPQESSFQPSQFLLLVGVPVASVLLLAQCLRWHCPRRLLGACWTLNGQEEPVSQPTPQLENEVSRQHLPATLPEMVAFYQELHTPTQGQTMVRQLMHKLLVFSAREVDHRGGCLMLQDTGISLLIPPGAVAVGRQERVSLILVWDLSDAPSLSQAQGLVSPVVACGPHGASFLKPCTLTFKHCAEQPSHARTYSSNTTLLDAKVWRPLGRPGAHASRDECRIHLSHFSLYTCVLEAPVGREARKWLQLAVFCSPLVPGQSHLQLRIYFLNNTPCALQWALTNEQPHGGRLRGPCQLFDFNGARGDQCLKLTYISEGWENVDDSSCQLVPHLHIWHGKCPFRSFCFRRKAADENEDCSALTNEIIVTMHTFQDGLETKYMEILRFQASEEESWAAPPPVSQPPPCNRLPPELFEQLRMLLEPNSITGNDWRGLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQELHYLMTVMERLDCASAIQNYLSGTHGGSPGPERGGARDNQGLELDEKL
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分子量
82.72 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UNC5CL (Uncoordinated-5 homolog C-like) is a member of the UNC5 family of receptors, known for their roles in neuronal development and guidance. Emerging research highlights UNC5CL's potential involvement in various physiological and pathological processes, including cell migration, apoptosis, and the nervous system's response to injury. Its association with developmental disorders and neurodegenerative diseases has prompted an increased interest in understanding its molecular functions and signaling pathways. Researchers have been particularly focused on the generation of recombinant UNC5CL protein to facilitate detailed structural and functional studies. By producing this protein through recombinant DNA technology, scientists aim to elucidate its interactions with ligands, characterize its structural properties, and investigate its role in cellular processes. Moreover, studying UNC5CL in a recombinant form allows for precise manipulation of its expression levels, which can provide insights into its function in both normal and disease states. This research is crucial for exploring potential therapeutic targets, as modulation of UNC5CL signaling may offer novel strategies for treating conditions linked to its dysregulation. Overall, the investigation of UNC5CL recombinant proteins is a significant step toward unveiling the complexities of its biological roles and potential implications in health and disease.
