Analytical Data
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基因名
FLJ14981
- Application
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别名
MPND. FLJ14981. hCG_2004608
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
W4VSR2
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表达区间
1-471aa
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氨基酸序列
MAAPEPLSPAGGAGEEAPEEDEDEAEAEDPERPNAGAGGGRSGGGGSSVSGGGGGGGAGAGGCGGPGGALTRRAVTLRVLLKDALLEPGAGVLSIYYLGKKFLGDLQPDGRIMWQETGQTFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKATWLRLHQLHTPATAADESPASEGEEEELLMEEEEEDVLAGVSAEDKSRRPLGKSPSEPAHPEATTPGKRVDSKIRVPVRYCMLGSRDLARNPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHSHLTRSEVVGYLGGRWDVNSQMLTVLRAFPCRSRLGDAETAAAIEEEIYQSLFLRGLSLVGWYHSHPHSPALPSLQDIDAQMDYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKISPFWVMPPPEMLLVEFYKGSPDLVRLQEPWSQEHTYLDKLKISLASRTPKDQSLCHVLEQVCGVLKQGS
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分子量
77.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FLJ14981, now officially designated as “FAM120A,” is a gene that encodes a protein involved in various cellular processes, particularly in maintaining cellular homeostasis and responding to stress. Initially, it was identified for its potential role in regulating the proliferation and differentiation of cells, drawing attention for its implications in developmental biology and cancer research. The importance of FLJ14981 in signal transduction pathways highlights its potential as a target for therapeutic interventions. Studies have suggested that FLJ14981 interacts with key molecular pathways, such as the mTOR and PI3K/Akt pathways, which are crucial in metabolic regulation and cell survival. Further investigation into the expression patterns and functional roles of FLJ14981 has unveiled its involvement in cellular stress responses, apoptosis, and oncogenesis. Importantly, researchers have been focusing on recombinantly producing FLJ14981 to elucidate its biochemical properties, understand its structural features, and explore its potential as a biomarker or therapeutic target in diseases. The recombinant protein's availability allows for detailed functional assays and manipulations to assess its role in various cellular contexts, paving the way for novel insights into disease mechanisms and therapeutic strategies.
