Analytical Data
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Gene name
FIGLA
- Application
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Alternative Names
FIGLA; BHLHC8Factor in the germline alpha; FIGalpha; Class C basic helix-loop-helix protein 8; bHLHc8; Folliculogenesis-specific basic helix-loop-helix protein; Transcription factor FIGa
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6QHK4
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Expression Region
1-219aa
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AA Sequence
MDPAPGVLDPRAAPPALLGTPQAEVLEDVLREQFGPLPQLAAVCRLKRLPSGGYSSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKDSKKQDPDEQSYSNNSSESHTSSARQLSRNITQHISCAFGLKNEEEGPWADGGSGEPAHACRHSVMSTTEIISPTRSLDRFPEVELLSHRLPQV
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Molecular Weight
51.04 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FIGLA (Fertility-Related Gene with an Intronic Location) is a transcription factor primarily expressed in the ovary and plays a crucial role in the regulation of oocyte development and fertility. Its discovery has drawn significant interest due to its involvement in reproductive biology and its potential implications for understanding infertility. FIGLA functions by binding to specific DNA sequences, thereby regulating the expression of target genes essential for folliculogenesis and oocyte maturation. In recent years, research has focused on the role of FIGLA in various reproductive disorders and its potential as a biomarker for ovarian reserve. Additionally, studies have explored its interactions with other key transcription factors, providing insight into the complex regulatory networks governing fertility. Advanced techniques such as CRISPR/Cas9 gene editing, RNA sequencing, and proteomics have further enhanced our understanding of FIGLA's mechanisms of action. Overall, the exploration of FIGLA as a recombinant protein not only holds promise for elucidating the molecular basis of fertility but also for developing targeted therapies in reproductive medicine, presenting exciting avenues for future research.
