Analytical Data
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Gene name
ITFG1
- Application
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Alternative Names
ITFG1；INO80H；NMP238；TIP49；RuvB-like 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TB96
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Expression Region
1-612aa
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AA Sequence
MAAAGRLPSSWALFSPLLAGLALLGVGPVPARALHNVTAELFGAEAWGTLAAFGDLNSDKQTDLFVLRERNDLIVFLADQNAPYFKPKVKVSFKNHSALITSVVPGDYDGDSQMDVLLTYLPKNYAKSELGAVIFWGQNQTLDPNNMTILNRTFQDEPLIMDFNGDLIPDIFGITNESNQPQILLGGNLSWHPALTTTSKMRIPHSHAFIDLTEDFTADLFLTTLNATTSTFQFEIWENLDGNFSVSTILEKPQNMMVVGQSAFADFDGDGHMDHLLPGCEDKNCQKSTIYLVRSGMKQWVPVLQDFSNKGTLWGFVPFVDEQQPTEIPIPITLHIGDYNMDGYPDALVILKNTSGSNQQAFLLENVPCNNASCEEARRMFKVYWELTDLNQIKDAMVATFFDIYEDGILDIVVLSKGYTKNDFAIHTLKNNFEADAYFVKVIVLSGLCSNDCPRKITPFGVNQPGPYIMYTTVDANGYLKNGSAGQLSQSAHLALQLPYNVLGLGRSANFLDHLYVGIPRPSGEKSIRKQEWTAIIPNSQLIVIPYPHNVPRSWSAKLYLTPSNIVLLTAIALIGVCVFILAIIGILHWQEKKADDREKRQEAHRFHFDAM
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Molecular Weight
68.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The ITFG1 protein, also known as Immunoglobulin Tail Interacting Protein 1, has garnered attention in the field of molecular biology due to its potential role in immune response regulation and cellular signaling. Emerging evidence suggests that ITFG1 plays a crucial part in the immunological synapse formation and T-cell activation, which are vital processes in the adaptive immune system. Dysregulation of such proteins can lead to autoimmune diseases and cancer, highlighting the need for a deeper understanding of ITFG1's structure and function. Research efforts have focused on the recombinant expression of ITFG1 to facilitate its characterization and study. By utilizing various expression systems, such as bacterial, yeast, or mammalian cells, scientists aim to produce sufficient quantities of the protein for functional assays, structural determination, and interaction studies. Such findings could offer insights into the molecular mechanisms underlying immune responses and inform therapeutic approaches for conditions linked to ITFG1 dysfunction. The successful reconstitution of ITFG1 in a laboratory setting not only enriches our understanding of its biological roles but also opens up avenues for potential drug development targeting immune-related disorders. Thus, ongoing research into ITFG1 remains a significant focus within immunology and cell biology.
