Analytical Data
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Gene name
FEZF2
- Application
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Alternative Names
FEZF2; FEZL; ZNF312; FKSG36Fez family zinc finger protein 2; Forebrain embryonic zinc finger-like protein 2; Zinc finger protein 312; Zinc finger protein Fez-like
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TBJ5
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Expression Region
1-459aa
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AA Sequence
MASSASLETMVPPACPRAGASPATSKTLAFSIERIMAKTSEPRAPFEPRPGALEADGSQGKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSELWKSSLRAGGGGGGGGGGGGGGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLTASGSLYYFNYLDSTAYPPSELLSGHLFPSGLLNAQAPAALAAHPKLFLLENAKLAGLAADKFPHPAPYPHKERLPAPLEQVLKENWALTAERGGVKGHSKLPGGSADGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDSVGPAAPSAKDLTRTVQS
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Molecular Weight
75.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FEZF2 (Fez Family Zinc Finger 2) is a crucial transcription factor predominantly expressed in neuronal tissues, playing a vital role in the development and differentiation of the central nervous system. Research has highlighted its involvement in regulating neurogenesis and influencing neuronal identity by orchestrating the expression of key target genes during brain development. Abnormalities in FEZF2 expression have been linked to various neurological disorders, underscoring its significance in neurodevelopmental processes. The recombinant FEZF2 protein has garnered attention for its potential use in studying molecular mechanisms underlying neuronal development and function. By producing this protein in a controlled laboratory environment, researchers can investigate its structural properties, binding capabilities, and interaction with other proteins. Understanding FEZF2’s role at a molecular level can provide insights into its contributions to brain disorders, potentially leading to novel therapeutic strategies. The study of FEZF2 and its recombinant forms is essential for dissecting complex neurodevelopmental pathways and ultimately aims to enhance our understanding of brain function and dysfunction.
