Analytical Data
-
Gene name
TUBD1
- Application
-
Alternative Names
Delta tubulin; Delta-tubulin; FLJ12709; TBD_HUMAN; TUBD; TUBD1; Tubulin delta chain
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9UJT1
-
Expression Region
1-453 aa
-
AA Sequence
MSIVTVQLGQ CGNQIGFEVF DALLSDSHSS QGLCSMRENE AYQASCKERF FSEEENGVPI ARAVLVDMEP KVINQMLSKA AQSGQWKYGQ HACFCQKQGS GNNWAYGYSV HGPRHEESIM NIIRKEVEKC DSFSGFFIIM SMAGGTGSGL GAFVTQNLED QYSNSLKMNQ IIWPYGTGEV IVQNYNSILT LSHLYRSSDA LLLHENDAIH KICAKLMNIK QISFSDINQV LAHQLGSVFQ PTYSAESSFH YRRNPLGDLM EHLVPHPEFK MLSVRNIPHM SENSLAYTTF TWAGLLKHLR QMLISNAKME EGIDRHVWPP LSGLPPLSKM SLNKDLHFNT SIANLVILRG KDVQSADVEG FKDPALYTSW LKPVNAFNVW KTQRAFSKYE KSAVLVSNSQ FLVKPLDMIV GKAWNMFASK AYIHQYTKFG IEEEDFLDSF TSLEQVVASY CNL
-
Molecular Weight
51.0 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TUBD1 (tubulin-dimerization-associated protein 1) is a crucial protein involved in the regulation of microtubule dynamics, playing a significant role in cell division and overall cellular structure. Understanding TUBD1's function has become increasingly important due to its implications in various biological processes and potential links to diseases, including cancer. Research has shown that TUBD1 interacts with tubulin, promoting its dimerization, which is essential for the formation and stabilization of microtubules. Abnormal expression or mutations in TUBD1 can lead to improper microtubule assembly and function, contributing to oncogenesis and tumor progression. As a result, TUBD1 has garnered attention as a potential biomarker for cancer diagnosis and a therapeutic target for treatment strategies aimed at restoring normal microtubule function. The generation of recombinant TUBD1 protein allows for detailed studies of its structure and function, providing insights into its role in microtubule dynamics. Through techniques such as X-ray crystallography and biochemical assays, researchers aim to elucidate the molecular mechanisms underlying TUBD1's interactions with tubulin and other associated proteins. This knowledge could pave the way for novel therapeutic approaches in cancer and other diseases linked to microtubule dysfunction, highlighting the significance of TUBD1 in cellular biology and its potential impact on future medical advancements.
