Analytical Data
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Gene name
TSC22D2
- Application
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Alternative Names
TSC22D2; KIAA0669; TILZ4; TSC22 domain family Protein 2; TSC22-related-inducible leucine zipper Protein 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75157
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Expression Region
1-780 aa
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AA Sequence
MSKMPAKKKS CFQITSVTTA QVATSITEDT ESLDDPDESR TEDVSSEIFD VSRATDYGPE EVCERSSSEE TLNNVGDAET PGTVSPNLLL DGQLAAAAAA PANGGGVVSA RSVSGALAST LAAAATSAPA PGAPGGPQLA GSSAGPVTAA PSQPPTTCSS RFRVIKLDHG SGEPYRRGRW TCMEYYERDS DSSVLTRSGD CIRHSSTFDQ TAERDSGLGA TGGSVVVVVA SMQGAHGPES GTDSSLTAVS QLPPSEKMSQ PTPAQPQSFS VGQPQPPPPP VGGAVAQSSA PLPPFPGAAT GPQPMMAAAQ PSQPQGAGPG GQTLPPTNVT LAQPAMSLPP QPGPAVGAPA AQQPQQFAYP QPQIPPGHLL PVQPSGQSEY LQQHVAGLQP PSPAQPSSTG AAASPATAAT LPVGTGQNAS SVGAQLMGAS SQPSEAMAPR TGPAQGGQVA PCQPTGVPPA TVGGVVQPCL GPAGAGQPQS VPPPQMGGSG PLSAVPGGPH AVVPGVPNVP AAVPAPSVPS VSTTSVTMPN VPAPLAQSQQ LSSHTPVSRS SSIIQHVGLP LAPGTHSAPT SLPQSDLSQF QTQTQPLVGQ VDDTRRKSEP LPQPPLSLIA ENKPVVKPPV ADSLANPLQL TPMNSLATSV FSIAIPVDGD EDRNPSTAFY QAFHLNTLKE SKSLWDSASG GGVVAIDNKI EQAMDLVKSH LMYAVREEVE VLKEQIKELV ERNSLLEREN ALLKSLSSND QLSQLPTQQA NPGSTSQQQA VIAQPPQPTQ PPQQPNVSSA
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Molecular Weight
79.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The TSC22D2 protein, a member of the TSC22 domain protein family, has garnered interest due to its potential roles in various biological processes, including cellular stress response, immune regulation, and cancer progression. Research indicates that TSC22D2 may function as a transcriptional regulator, influencing gene expression in response to environmental stimuli. Its expression is often altered in pathological conditions such as inflammation and cancer, suggesting it could play a role in tumorigenesis and the immune response. The study of recombinant TSC22D2 provides valuable insights into its structure-function relationships and interactions with other cellular components. Understanding the mechanisms by which TSC22D2 exerts its effects can unveil novel therapeutic targets for diseases associated with dysregulated TSC22D2 activity. Furthermore, recombinant TSC22D2 can serve as a tool for investigating its biological functions and interactions, potentially leading to advances in treatments for cancers and autoimmune disorders. Current research focuses on elucidating its signaling pathways and post-translational modifications, which may enhance our understanding of its regulatory mechanisms in health and disease. Overall, the investigation of TSC22D2 and its recombinant forms is crucial for unraveling its potential as a biomarker and therapeutic target in various clinical settings.
