Analytical Data
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Gene name
ZNF496
- Application
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Alternative Names
NIZP1; NSD1 (nuclear receptor binding SET-domain containing 1)-interacting zinc finger Protein 1; NSD1-interacting zinc finger Protein 1; Zinc finger Protein 496; Zinc finger Protein with KRAB and SCAN domains 17; ZKSCAN17; ZN496_HUMAN; ZNF496
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96IT1
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Expression Region
1-587 aa
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AA Sequence
MPTALCPRVLAPKESEEPRKMRSPPGENPSPQGELPSPESSRRLFRRFRYQEAAGPREALQRLWDLCGGWLRPERHTKEQILELLVLEQFLAILPREIQSWVRAQEPESGEQAVAAVEALEREPGRPWQWLKHCEDPVVIDDGDSPLDQEQEQLPVEPHSDLAKNQDAQPITLAQCLGLPSRPPSQLSGDPVLQDAFLLQEENVRDTQQVTTLQLPPSRVSPFKDMILCFSEEDWSLLDPAQTGFYGEFIIGEDYGVSMPPNDLAAQPDLSQGEENEPRVPELQDLQGKEVPQVSYLDSPSLQPFQVEERRKREELQVPEFQACPQTVVPQNTYPAGGNPRSLENSLDEEVTIEIVLSSSGDEDSQHGPYCTEELGSPTEKQRSLPASHRSSTEAGGEVQTSKKSYVCPNCGKIFRWRVNFIRHLRSRREQEKPHECSVCGELFSDSEDLDGHLESHEAQKPYRCGACGKSFRLNSHLLSHRRIHLQPDRLQPVEKREQAASEDADKGPKEPLENGKAKLSFQCCECGKAFQRHDHLARHRSHFHLKDKARPFQCRYCVKSFTQNYDLLRHERLHMKRRSKQALNSY
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Molecular Weight
93.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF496, a member of the zinc finger protein family, has garnered significant attention in recent years due to its potential roles in various biological processes, including gene regulation and cellular differentiation. Research indicates that ZNF496 may play a critical role in developmental pathways, particularly in the context of stem cell biology and tissue homeostasis. Its unique structure allows for specific interactions with DNA and other proteins, which are essential for modulating transcriptional networks. Furthermore, emerging evidence suggests that ZNF496 could be implicated in disease mechanisms, such as cancer progression and metabolic disorders, highlighting its potential as a therapeutic target. The generation of recombinant ZNF496 protein is vital for elucidating its functional properties and understanding its molecular mechanisms. By utilizing techniques such as recombinant DNA technology, researchers aim to produce sufficient quantities of pure ZNF496 for biochemical assays, structural studies, and functional analyses. Investigating the interactions of ZNF496 with other cellular components will provide deeper insights into its biological significance and potential applications in regenerative medicine and targeted therapies. This ongoing research seeks to clarify the multifaceted roles of ZNF496 in health and disease, paving the way for innovative strategies in the management of related pathologies.
