Analytical Data
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Gene name
EFNA2
- Application
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Alternative Names
EFNA2；EPLG6；LERK6；Ephrin-A2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43921
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Expression Region
1-213aa
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AA Sequence
MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHA GAGDDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHA SCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYY ISATPPNAVDRPCLRLKVYVRPTNETLYEAPEPIFTSNNSCSSPGGCRLF LSTIPVLWTLLGS
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Molecular Weight
50 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EFNA2, a member of the Ephrin-A family, plays a crucial role in various biological processes, including neural development, cell adhesion, and tissue patterning. As a ligand for Eph receptors, EFNA2 is involved in bidirectional signaling that influences cell migration, differentiation, and boundaries in developing tissues. Research has demonstrated its significance in neurodevelopmental disorders, cancer progression, and other pathological conditions, highlighting its potential as a therapeutic target. The recombinant production of EFNA2 allows for detailed studies of its structure-function relationships, interactions with Eph receptors, and downstream signaling pathways. By generating and characterizing EFNA2 recombinant protein, researchers aim to unravel its specific roles in cellular processes and contribute to the development of targeted therapies for diseases linked to aberrant Ephrin signaling. Understanding EFNA2's mechanisms may pave the way for innovative approaches in regenerative medicine and targeted drug design.
