Analytical Data
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Gene name
TRIM61
- Application
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Alternative Names
TRIM61; RNF35; Putative tripartite motif-containing Protein 61; RING finger Protein 35
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5EBN2
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Expression Region
1-209 aa
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AA Sequence
MEFVTALADL RAEASCPICL DYLKDPVTIS CGHNFCLSCI IMSWKDLHDS FPCPFCHFCC PERKFISNPQ LGSLTEIAKQ LQIRSKKRKR QEEKHVCKKH NQVLTFFCQK DLELLCPRCS LSTDHQHHCV WPIKKAASYH RKKLEEYNAP WKERVELIEK VITMQTRKSL ELKKKMESPS VTRLECSCTI SAHFNLRLPG SSDSSASGS
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Molecular Weight
24.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRIM61, a member of the tripartite motif (TRIM) family of proteins, has garnered significant attention in recent years due to its potential roles in diverse biological processes and diseases. This family is characterized by the presence of a RING domain, B-box, and coiled-coil region, which are involved in protein interactions and ubiquitination processes. Research indicates that TRIM61 may play a pivotal role in regulating cellular functions such as apoptosis, cell proliferation, and immune responses. Furthermore, emerging evidence suggests that TRIM61 is implicated in various pathologies, including cancer, where it may influence tumor progression and metastasis. Its expression patterns and molecular mechanisms are of particular interest, leading to investigations into the therapeutic potential of targeting TRIM61 activities in disease contexts. The recombinant production of TRIM61 protein has facilitated these studies, enabling researchers to explore its structural and functional characteristics in detail. By understanding the interactions and signaling pathways mediated by TRIM61, scientists aim to elucidate its contributions to disease mechanisms and identify novel strategies for intervention in TRIM61-related disorders. This groundwork is essential for the development of potential biomarkers and therapeutic targets, underscoring the importance of ongoing research into this intriguing protein.
