Analytical Data
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Gene name
ZNF447
- Application
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Alternative Names
ZSCAN18; ZNF447; Zinc finger and SCAN domain-containing Protein 18; Zinc finger Protein 447
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TBC5
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Expression Region
1-510 aa
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AA Sequence
MLPLEKAFASPRSSPAPPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFREFVYQEAAGPHQTLARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHMDPLLLPGELASPSQALGAGEIPAPSETPWLSPDPLFLEQRRVREAKTEEDGPANTEQKLKSFPEDPQHLGEWGHLDPAEENLKSYRKLLLWGYQLSQPDAASRLDTEELRLVERDPQGSSLPEGGRRQESAGCACEEAAPAGVLPELPTEAPPGDALADPPSGTTEEEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKRPHPEDGDEQSLEGVSSSGDSAGLEAGQGPGADEPGLSRGKPYACGECGEAFAWLSHLMEHHSSHGGRKRYACQGCWKTFHFSLALAEHQKTHEKEKSYALGGARGPQPSTREAQAGARAGGPPESVEGEAPPAPPEAQR
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Molecular Weight
81.84 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF447 (Zinc Finger Protein 447) is a relatively less-studied member of the zinc finger protein family, which is known for its roles in DNA binding, transcription regulation, and various cellular processes. The interest in ZNF447 has grown in recent years due to its potential implications in gene regulation, embryonic development, and disease pathogenesis, particularly in cancer. Emerging evidence suggests that ZNF447 may contribute to transcriptional networks that regulate key biological pathways, making it a candidate for functional studies. The expression profile of ZNF447 in different tissues and its regulation under various physiological and pathological conditions further highlights its significance. Recent advancements in recombinant protein technology have enabled researchers to produce ZNF447 in a laboratory setting, facilitating biochemical characterizations and functional assays. The availability of recombinant ZNF447 protein paves the way for elucidating its molecular mechanisms, interaction partners, and biological functions. Studying ZNF447 in a controlled environment could provide insights into its role in cellular processes and its potential as a therapeutic target or biomarker in diseases, including cancers where aberrant expression of zinc finger proteins has been linked to tumorigenesis. As research progresses, a better understanding of ZNF447's function and its pathways could open up new avenues for therapeutic interventions in related disorders.
