Cat: PAX2000-12866

Recombinant Human ZNF432 Protein,His

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Analytical Data

  • Gene name

    ZNF432

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ZNF432; KIAA0798Zinc finger Protein 432

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O94892

  • Expression Region

    1-652 aa

  • AA Sequence

    MINAQELLTL EDVTVEFTWE EWQLLGPFQK DLYRDVMLEI YSNLLSMGYQ VSKPDALSKL ERGEEPWTME DERHSRICPE NNEVDDHLQD HLENQRMLKS VEQYHEHNAF GNTASQTKSL CLFRENHDTF ELYIKTLKSN LSLVNQNKSC EINNSTKFSG DGKSFLHGNY EELYSAAKFS VSTKANSTKS QVSKHQRTHE IEKNHVCSEC GKAFVKKSQL TDHERVHTGE KPYGCTLCAK VFSRKSRLNE HQRIHKREKS FICSECGKVF TMKSRLIEHQ RTHTGEKPYI CNECGKGFPG KRNLIVHQRN HTGEKSYICS ECGKGFTGKS MLIIHQRTHT GEKPYICSEC GKGFTTKHYV IIHQRNHTGE KPYICNECGK GFTMKSRMIE HQRTHTGEKP YICSECGKGF PRKSNLIVHQ RNHTVEKSYL CSECGKGFTV KSMLIIHQRT HTGEKPYTCS ECGKGFPLKS RLIVHQRTHT GEKPYRCSEC GKGFIVNSGL MLHQRTHTGE KPYICNECGK GFAFKSNLVV HQRTHTGEKP FMCSECGKGF TMKRYLIVHQ QIHTEEKSCI CSECGRGFAK ETELALHKQV HTGEKPYGCN ECGKGFTMKS RLIVHQRTHT GEKPFVCSEC RKAFSSKRNL IVHQRTHNGN KP

  • Molecular Weight

    74.8 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZNF432, a member of the zinc finger protein family, is recognized for its potential roles in transcriptional regulation and various cellular processes, including development and cell differentiation. Research into ZNF432 has gained momentum due to its implications in pathophysiological conditions, such as cancer and genetic disorders, where aberrant expression or mutations may disrupt normal cellular functions. The study of ZNF432 recombinant proteins has become crucial for understanding its structure-function relationships, as well as its interactions with DNA and other proteins. Through techniques such as X-ray crystallography and NMR spectroscopy, researchers aim to elucidate the precise mechanisms by which ZNF432 regulates gene expression. Additionally, recombinant ZNF432 can serve as a valuable tool in functional assays, enabling scientists to investigate its role in signaling pathways and gene regulatory networks. Understanding ZNF432's function at a molecular level could provide insights into potential therapeutic targets for diseases associated with its dysregulation, paving the way for innovative approaches in gene therapy and molecular medicine. Thus, the increasing focus on ZNF432 and its recombinant form underscores its significance in both basic and applied biomedical research.

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