Analytical Data
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Gene name
ARNTL
- Application
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Alternative Names
ARNTL;ARNTL;BHLHE5;MOP3;Basic helix-loop-helix ARNT-like Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O00327
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Expression Region
1-625aa
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AA Sequence
MADQRMDISSTISDFMSPGPTDLLSSSLGTSGVDCNRKRKGSSTDYQESM DTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVP TCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHL ILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKD IAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCR MKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDED NEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFV FVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITT NCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDP TFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAE EIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSS GLLSGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMA VIMSLLEADAGLGGPVDFSDLPWPL
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Molecular Weight
94 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like), also known as BMAL1, is a key regulator of the circadian rhythm, influencing various physiological processes in mammals. Research into ARNTL has gained momentum due to its critical role in the expression of clock genes and its involvement in the regulation of metabolic processes, thereby linking circadian biology with health and disease. Recombining ARNTL protein for study allows researchers to explore its function in cellular mechanisms, particularly its interaction with other transcription factors within the circadian clock network. This research is essential for understanding sleep disorders, metabolic syndromes, and other conditions linked to circadian disruptions. Additionally, the manipulation of ARNTL through recombinant protein techniques could lead to potential therapeutic interventions, targeting diseases that stem from circadian misalignment. As the global prevalence of such conditions rises, investigating the molecular foundations of circadian regulation through ARNTL is becoming increasingly important, thereby fueling its role in biomedical research and therapeutic development.











