Cat: PAX2000-12841

Recombinant Human ZNF358 Protein,His

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Analytical Data

  • Gene name

    ZNF358

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ZFEND; Zinc finger Protein 358; ZN358_HUMAN; ZNF358

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NW07

  • Expression Region

    1-568 aa

  • AA Sequence

    MRRSVLVRNP GHKGLRPVYE ELDSDSEDLD PNPEDLDPVS EDPEPDPEDL NTVPEDVDPS YEDLEPVSED LDPDAEAPGS EPQDPDPMSS SFDLDPDVIG PVPLILDPNS DTLSPGDPKV DPISSGLTAT PQVLATSPAV LPAPASPPRP FSCPDCGRAF RRSSGLSQHR RTHSGEKPYR CPDCGKSFSH GATLAQHRGI HTGARPYQCA ACGKAFGWRS TLLKHRSSHS GEKPHHCPVC GKAFGHGSLL AQHLRTHGGP RPHKCPVCAK GFGQGSALLK HLRTHTGERP YPCPQCGKAF GQSSALLQHQ RTHTAERPYR CPHCGKAFGQ SSNLQHHLRI HTGERPYACP HCSKAFGQSS ALLQHLHVHS GERPYRCQLC GKAFGQASSL TKHKRVHEGA AAAAAAAAAA AAAAAAGLGL GPGLSPASMM RPGQVSLLGP DAVSVLGSGL GLSPGTSSGR NPDPGSGPGT LPDPSSKPLP GSRSTPSPTP VESSDPKAGH DAGPDLVPSP DLDPVPSPDP DPVPSPDPNP VSCPDPCSPT RGTVSPALPT GESPEWVQEQ GALLGPDG

  • Molecular Weight

    59.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZNF358, a member of the zinc finger protein family, plays a crucial role in various cellular processes, including transcriptional regulation, DNA damage response, and cell differentiation. Recent studies have highlighted its potential involvement in several diseases, particularly in cancer, where abnormal expression of ZNF358 can influence tumor progression and cellular stress responses. The understanding of ZNF358's functional mechanisms and its protein interactions is essential for elucidating its biological roles. Recombinant ZNF358 protein production has emerged as a valuable tool for dissecting its functions through in vitro studies and for exploring its potential as a therapeutic target. By generating a stable and functional form of ZNF358, researchers aim to investigate its binding properties, post-translational modifications, and interactions with other proteins within cellular signaling pathways. Collectively, this research contributes to a deeper understanding of ZNF358’s role in health and disease, paving the way for innovative strategies in diagnostics and therapeutics.

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