Analytical Data
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基因名
TRGV3
- Application
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别名
TRGV3; TCRGV3; T cell receptor gamma variable 3; T-cell receptor gamma V-gamma-1.1 region
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P03979
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表达区间
21-136 aa
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氨基酸序列
NLEGRTKSVT RQTGSSAEIT CDLTVTNTFY IHWYLHQEGK APQRLLYYDV STARDVLESG LSPGKYYTHT PRRWSWILRL QNLIENDSGV YYCATWDRXK NYYKKLFGSG TTLVVT
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分子量
13.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRGV3 is a member of the T cell receptor gamma (TCRγ) gene family, playing a pivotal role in the immune response, particularly in the context of γδ T cells. These cells are a unique subset of T lymphocytes that recognize a wide range of antigens without the need for classical major histocompatibility complex (MHC) presentation. The study of TRGV3, alongside its associated TCR gene segments, has garnered attention due to its potential implications in immunotherapy and vaccine development, especially against cancers and infectious diseases. Recent advancements in molecular biology techniques have enabled researchers to explore the structure and function of TRGV3 recombinants, shedding light on their interaction with various antigens and potential therapeutic applications. Understanding the mechanisms by which TRGV3 contributes to T cell activation, differentiation, and tissue residency may pave the way for novel strategies in enhancing immune responses. Furthermore, its unique properties could be harnessed for biomarker discovery and the development of personalized immunotherapies. The ongoing research focuses on elucidating the biological functions of TRGV3, including its role in tumor immunity and protective responses against pathogens, thus highlighting its significance in the field of immunology.
