Analytical Data
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基因名
SLURP1
- Application
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别名
SLURP1；ARS；Secreted Ly-6/uPAR-related Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55000
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表达区间
23-103aa
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氨基酸序列
LKCYTCKEPMTSASCRTITRCKPEDTACMTTLVTVEAEYPFNQSPVVTRSCSSSCVATDPDSIGAAHLIFCCFRDLCNSEL
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分子量
10.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLURP1, a secreted protein predominantly expressed in the skin and nervous system, has garnered significant attention for its potential roles in various physiological and pathological processes. Initially identified as a neuromodulator in the peripheral nervous system, SLURP1 is believed to influence keratinocyte function and exhibit anti-inflammatory properties, making it a candidate for therapeutic exploration in skin-related conditions. Furthermore, its interactions with nicotinic acetylcholine receptors have raised interest in its implications for neurodegenerative diseases and pain modulation. Research has revealed that mutations in the SLURP1 gene are associated with certain genetic skin disorders, such as Mal de Meleda, further highlighting its importance in dermatology and genetics. The recombinant production of SLURP1 protein allows for extensive studies into its structure-function relationship, paving the way for elucidating its biological mechanisms. This could provide insights into its diverse roles and potential applications in drug development and treatment strategies for related diseases. Understanding SLURP1 at a molecular level could open new avenues in personalized medicine and targeted therapies, making it a compelling subject for ongoing research.
