Analytical Data
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基因名
COQ10B
- Application
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别名
COQ10B;Coenzyme Q-binding Protein COQ10 homolog B. mitochondrial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H8M1
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表达区间
38-238aa
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氨基酸序列
ASC GILMSRTLPL HTSILPKEIC ARTFFKITAP LINKRKEYSE RRILGYSMQE MYDVVSGVED YKHFVPWCKK SDVISKRSGY CKTRLEIGFP PVLERYTSVV TLVKPHLVKA SCTDGRLFNH LETIWRFSPG LPGYPRTCTL DFSISFEFRS LLHSQLATLF FDEVVKQMVA AFERRACKLY GPETNIPREL MLHEVHHT
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Coenzyme Q10 (CoQ10), also known as ubiquinone, is a critical lipophilic molecule present in the mitochondrial membrane, where it plays a vital role in the electron transport chain and ATP synthesis. Its antioxidant properties contribute to cellular protection against oxidative stress, and it is involved in various metabolic processes. The recombinant expression of CoQ10 biosynthetic enzymes, specifically the COQ10B gene, has garnered significant attention in recent years due to its potential applications in biotechnology and medicine. Studies have indicated that CoQ10 supplementation may benefit conditions like cardiovascular diseases, neurodegenerative disorders, and muscular dystrophies. However, the natural sourcing of CoQ10 is limited and expensive. To overcome this, researchers have been focusing on producing recombinant forms of CoQ10 through microbial fermentation or yeast systems, which provide a sustainable and cost-effective approach for large-scale production. Furthermore, understanding the functional properties of COQ10B and its interactions within the biosynthetic pathway enhances the potential for novel therapeutics and dietary supplements. Thus, research on COQ10B recombinant proteins not only holds promise for advancing our knowledge of CoQ10 metabolism but also for improving human health through the development of effective and accessible CoQ10 formulations.












