Cat: PA2000-7458

Recombinant Human FAM100A Protein,GST

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Analytical Data

  • Gene name

    FAM100A

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    UBALD1; FAM100A; PP11303UBA-like domain-containing protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8TB05

  • Expression Region

    1-177aa

  • AA Sequence

    MSVNMDELKH QVMINQFVLT AGCAADQAKQ LLQAAHWQFE TALSAFFQET NIPYSHHHHQ MMCTPANTPA TPPNFPDALT MFSRLKASES FHSGGSGSPM AATATSPPPH FPHAATSSSA ASSWPTAASP PGGPQHHQPQ PPLWTPTPPS PASDWPPLAP QQATSEPRAH PAMEAER

  • Molecular Weight

    45.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

FAM100A, also known as FAM100A protein or FAM100A homolog, is a member of the FAM100 protein family, characterized by its critical roles in cellular proliferation, differentiation, and apoptosis. Research has highlighted its potential involvement in various diseases, particularly cancer, where aberrant expression of FAM100A correlates with tumor progression and metastasis. Studies suggest that FAM100A may function as a regulator of key signaling pathways, including those related to cell cycle control and stress responses, which could explain its contribution to oncogenic processes. Furthermore, the interrogation of FAM100A's structure and function has the potential to uncover novel therapeutic targets. The recombinant expression of FAM100A protein enables researchers to perform detailed biochemical studies, elucidating its molecular interactions and biological functions. This research is crucial for understanding the precise mechanisms by which FAM100A influences cellular behavior and could pave the way for innovative strategies in cancer treatment and other diseases linked to its dysregulation. As interest in this protein continues to grow, ongoing studies will likely explore its roles in development and cellular homeostasis, solidifying FAM100A's status as a significant player in both basic and applied biomedical research.

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