Analytical Data
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基因名
ZNF289
- Application
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别名
ADP-ribosylation factor GTPase-activating Protein 2; ARF GAP 2; ARFG2_HUMAN; ARFGAP2; FLJ14576; FLJ26000; GTPase activating Protein ZNF289; GTPase-activating Protein ZNF289; IRZ; Nbla10535 ; Zfp289; Zinc finger Protein 289; Zinc finger Protein 289 ID1 regulated; ZNF289
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N6H7
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表达区间
2-521 aa
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氨基酸序列
AAEPNKTEI QTLFKRLRAV PTNKACFDCG AKNPSWASIT YGVFLCIDCS GVHRSLGVHL SFIRSTELDS NWNWFQLRCM QVGGNANATA FFRQHGCTAN DANTKYNSRA AQMYREKIRQ LGSAALARHG TDLWIDNMSS AVPNHSPEKK DSDFFTEHTQ PPAWDAPATE PSGTQQPAPS TESSGLAQPE HGPNTDLLGT SPKASLELKS SIIGKKKPAA AKKGLGAKKG LGAQKVSSQS FSEIERQAQV AEKLREQQAA DAKKQAEESM VASMRLAYQE LQIDRKKEEK KLQNLEGKKR EQAERLGMGL VSRSSVSHSV LSEMQVIEQE TPVSAKSSRS QLDLFDDVGT FASGPPKYKD NPFSLGESFG SRWDTDAAWG MDRVEEKEPE VTISSIRPIS ERATNRREVE SRSSGLESSE ARQKFAGAKA ISSDMFFGRE VDAEYEARSR LQQLSGSSAI SSSDLFGDMD GAHGAGSVSL GNVLPTADIA QFKQGVKSVA GKMAVLANGV MNSLQDRYGS Y
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分子量
56.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF289, a member of the zinc finger transcription factor family, has garnered interest in recent years due to its potential roles in various biological processes, including transcription regulation, DNA repair, and cellular differentiation. These transcription factors are characterized by their ability to interact with DNA in a sequence-specific manner, thereby influencing gene expression. Research has indicated that ZNF289 might play a critical role in regulating genes involved in cellular responses to stress and development. Moreover, dysregulation of ZNF289 expression has been linked to several diseases, including cancer, where it may affect tumor progression and metastasis. Consequently, the recombinant expression of ZNF289 serves as a valuable tool for investigating its functional mechanisms and interactions at the molecular level. By producing ZNF289 as a recombinant protein, researchers can study its structure, binding affinities, and specific targets, facilitating a deeper understanding of its biological roles. Investigating ZNF289 through recombinant technology not only enhances our knowledge of transcriptional regulation but also may reveal novel therapeutic targets for diseases associated with its dysregulation. These insights emphasize the importance of ZNF289 in gene regulation and its potential implications in health and disease.
