Analytical Data
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基因名
FAIM2
- Application
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别名
FAIM2; KIAA0950; LFG; LFG2; NMP35; TMBIM2; Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BWQ8
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表达区间
1-316aa
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氨基酸序列
MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE
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分子量
60.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FAIM2, or Fas apoptotic inhibitory molecule 2, is a member of the FAIM family that plays a crucial role in regulating apoptosis and cellular survival signaling pathways. Initially identified for its anti-apoptotic function, FAIM2 is of particular interest in the context of various diseases, including cancer and autoimmune disorders. Research has indicated that overexpression of FAIM2 can confer resistance to apoptosis in cancer cells, thereby contributing to tumorigenesis and cancer progression. Additionally, FAIM2 has been implicated in regulating immune responses, highlighting its potential as a therapeutic target for modulating immune-related conditions. Recent studies have focused on understanding the mechanisms by which FAIM2 exerts its effects, including its interactions with various signaling molecules and pathways. The development of recombinant FAIM2 protein has facilitated these investigations, allowing for detailed analysis of its structure, function, and role in disease. Furthermore, insights gained from FAIM2 research could lead to innovative therapeutic strategies aimed at enhancing apoptotic sensitivity in cancer therapy or modulating immune responses in autoimmune diseases. As the understanding of FAIM2 continues to evolve, it holds promise for the development of novel interventions that could improve patient outcomes in a range of pathological conditions.
