Analytical Data
-
Gene name
ZNF274
- Application
-
Alternative Names
ZNF274; ZKSCAN19; SP2114Neurotrophin receptor-interacting factor homolog; Zinc finger Protein 274; Zinc finger Protein HFB101; Zinc finger Protein with KRAB and SCAN domains 19; Zinc finger Protein zfp2; Zf2
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96GC6
-
Expression Region
1-653 aa
-
AA Sequence
MASRLPTAWS CEPVTFEDVT LGFTPEEWGL LDLKQKSLYR EVMLENYRNL VSVEHQLSKP DVVSQLEEAE DFWPVERGIP QDTIPEYPEL QLDPKLDPLP AESPLMNIEV VEVLTLNQEV AGPRNAQIQA LYAEDGSLSA DAPSEQVQQQ GKHPGDPEAA RQRFRQFRYK DMTGPREALD QLRELCHQWL QPKARSKEQI LELLVLEQFL GALPVKLRTW VESQHPENCQ EVVALVEGVT WMSEEEVLPA GQPAEGTTCC LEVTAQQEEK QEDAAICPVT VLPEEPVTFQ DVAVDFSREE WGLLGPTQRT EYRDVMLETF GHLVSVGWET TLENKELAPN SDIPEEEPAP SLKVQESSRD CALSSTLEDT LQGGVQEVQD TVLKQMESAQ EKDLPQKKHF DNRESQANSG ALDTNQVSLQ KIDNPESQAN SGALDTNQVL LHKIPPRKRL RKRDSQVKSM KHNSRVKIHQ KSCERQKAKE GNGCRKTFSR STKQITFIRI HKGSQVCRCS ECGKIFRNPR YFSVHKKIHT GERPYVCQDC GKGFVQSSSL TQHQRVHSGE RPFECQECGR TFNDRSAISQ HLRTHTGAKP YKCQDCGKAF RQSSHLIRHQ RTHTGERPYA CNKCGKAFTQ SSHLIGHQRT HNRTKRKKKQ PTS
-
Molecular Weight
74.1 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF274, a zinc finger protein, is part of a family of transcription factors that play crucial roles in gene regulation and cellular differentiation. Research into ZNF274 has revealed its involvement in various biological processes, including development, cell growth, and responses to environmental stimuli. It is particularly known for its function in the regulation of gene expression through its ability to bind to specific DNA sequences and modulate the transcription of target genes. Additionally, ZNF274 has been implicated in epigenetic regulation, influencing chromatin structure and thus the accessibility of gene promoters. Due to its potential role in various diseases, including cancer, understanding the mechanisms underlying ZNF274 activity is of significant interest. The recombinant protein of ZNF274 is produced to facilitate in vitro studies, allowing researchers to investigate its biochemical properties, interaction dynamics, and functional roles within cellular pathways. This research not only broadens our understanding of ZNF274's biological significance but also paves the way for potential therapeutic applications, as targeted modulation of its activity might offer novel strategies in disease treatment and gene therapy. As such, the study of ZNF274 recombinant protein continues to be an important area of exploration in molecular biology and medicine.
