Analytical Data
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基因名
TNFAIP1
- Application
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别名
TNFAIP1; BACURD2; EDP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation Protein 2; hBACURD2; BTB/POZ domain-containing Protein TNFAIP1; Protein B12; Tumor necrosis factor; alpha-induced Protein 1; endothelial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13829
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表达区间
1-316 aa
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氨基酸序列
MSGDTCLCPA SGAKPKLSGF KGGGLGNKYV QLNVGGSLYY TTVRALTRHD TMLKAMFSGR MEVLTDKEGW ILIDRCGKHF GTILNYLRDD TITLPQNRQE IKELMAEAKY YLIQGLVNMC QSALQDKKDS YQPVCNIPII TSLKEEERLI ESSTKPVVKL LYNRSNNKYS YTSNSDDHLL KNIELFDKLS LRFNGRVLFI KDVIGDEICC WSFYGQGRKL AEVCCTSIVY ATEKKQTKVE FPEARIYEET LNVLLYETPR VPDNSLLEAT SRSRSQASPS EDEETFELRD RVRRIHVKRY STYDDRQLGH QSTHRD
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分子量
36.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TNFAIP1, or Tumor Necrosis Factor Alpha Induced Protein 1, is a significant protein that plays a crucial role in cellular stress responses and inflammation. It is primarily induced by pro-inflammatory cytokines, particularly tumor necrosis factor-alpha (TNF-α), which is well-known for its involvement in immune response regulation and pathogenesis of various diseases, including autoimmune disorders and cancers. The TNFAIP1 protein has been implicated in modulating cell survival, apoptosis, and proliferation, making it a critical factor in both normal physiological and pathological processes. Recent studies have highlighted its potential as a biomarker for certain diseases, as well as a therapeutic target due to its role in modulating inflammation and cellular stress responses. The recombinant expression of TNFAIP1 has enabled researchers to explore its functional mechanisms in detail, facilitating the study of its interactions with other signaling pathways. Understanding the precise roles of TNFAIP1 in various biological contexts may lead to novel therapeutic strategies for managing inflammatory diseases and cancer, making it a focal point of ongoing research in immunology and cell biology. This background underlines the importance of developing recombinant TNFAIP1 for further investigation into its structure-function relationships, which could pave the way for innovative treatments targeting TNFAIP1-related pathways.
