Analytical Data
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Gene name
TMOD2
- Application
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Alternative Names
TMOD2; NTMOD; Tropomodulin-2; Neuronal tropomodulin; N-Tmod
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NZR1
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Expression Region
1-351 aa
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AA Sequence
MALPFQKELE KYKNIDEDEL LGKLSEEELK QLENVLDDLD PESAMLPAGF RQKDQTQKAA TGPFDREHLL MYLEKEALEQ KDREDFVPFT GEKKGRVFIP KEKPIETRKE EKVTLDPELE EALASASDTE LYDLAAVLGV HNLLNNPKFD EETANNKGGK GPVRNVVKGE KVKPVFEEPP NPTNVEISLQ QMKANDPSLQ EVNLNNIKNI PIPTLREFAK ALETNTHVKK FSLAATRSND PVAIAFADML KVNKTLTSLN IESNFITGTG ILALVEALKE NDTLTEIKID NQRQQLGTAV EMEIAQMLEE NSRILKFGYQ FTKQGPRTRV AAAITKNNDL VRKKRVEADR R
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Molecular Weight
39.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMOD2, or Tropomodulin 2, is a member of the tropomodulin family, which plays a critical role in actin filament stabilization and cellular structure maintenance. This protein is primarily expressed in muscle tissues and has been implicated in various cellular processes, including muscle contraction and maintenance of the cytoskeleton. Research on TMOD2 has gained momentum due to its potential implications in muscle-related disorders and diseases, such as cardiomyopathies and skeletal muscle myopathies. Understanding the structure and function of TMOD2 at the molecular level is essential for elucidating its role in muscle physiology and pathophysiology. Recent advancements in recombinant protein technology have enabled the production of TMOD2 in a controlled laboratory setting, allowing for detailed studies of its biochemical properties, interaction with actin filaments, and regulatory mechanisms. This research not only enhances our understanding of TMOD2’s function but also offers potential therapeutic avenues, as targeting tropomodulin-related pathways could lead to novel treatments for muscle degenerative diseases. As such, TMOD2 recombinant protein studies are vital in bridging the gap between basic research and clinical applications, making it a significant focus in the fields of biochemistry, molecular biology, and medicine.
